• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The present invention provides a specimen test slide comprising a specimen-receiving sheet (1) carrying guiac sandwiched between a front and rear panel (2) and (3) in which the slide can be opened to the front (4, 5, 6) to expose a guaiac-carrying part of the sheet and to the rear (11), to expose the rear of that part of the sheet exposed to the front, and having 2,6-di-tert-butyl-p-cresol (7) on at least part of the inner surface of that part of the slide overlying to the front or to the rear of the part of the sheet which is exposed.
    公开号:SU1466664A3
    申请号:SU823385950
    申请日:1982-01-28
    公开日:1989-03-15
    发明作者:Бернсайд Детвейлер Майкл；Джозеф Лоренц Поль；Вильям Таупслей Чарльз
    申请人:Смитклайн Инструменте, Инк. (US)；
    IPC主号:
    专利说明:

    The invention relates to medicine and can be used to place samples for the hidden presence of blood in the test solution or suspension.
    The purpose of the invention is to increase the shelf life of a slide for analysis by treating the inner surface of the rotary cores with which the slide is provided with a 1.5-252% solution or suspension of 2,6-di-tert-butyl-p-crezole prepared in a lacquer or acetone.
    PREMIUME 1. 2,6-di-tert-butyl-p-cresol (BHT) is dissolved in acetone at a concentration of 22.5 µmol and the inner surface of the Hemocalte slide is coated with the resulting solution. For comparison, five well-known antioxidants are used, solutions of which were also treated with Hemocalte tablets.
    After evaporation of the solvent, the slides are closed, exposed to nitrogen dioxide in air in an amount of 2 gp, and the development time of the blue color in each slide is determined,
    The results are shown in table 1.
    The results show that, even under complicated conditions, BHT prevents the appearance of blue colored paper on the slide.
    1-Lenilsemikarbazid, protecting the slide when directly applied to gw paper, does not have an effect when applied to the inner surface of the slide krygga.
    EXAMPLE 2. A BHT compound is dissolved in a lacquer and applied to the inside surface of a slide cover, after which the closed slide is exposed to air under normal conditions.
    The results are shown in table 2 ..

    but
    Lacquer is preferably used as a carrier; a solution of phenolic resin or drying oil (Chine wood oil, linseed oil) in a volatile solvent (alcohol).
    Similar results are obtained when using a solution of BHT in a lacquer or acetone at a concentration of 2.2% (10 g of BHT is added to 454 g of solvent).
    Formula
    and
    acquisitions
    The method of stabilizing a slide for analyzing the hidden presence of blood by using panels equipped with holes and swiveling lids that cover said holes, which, in order to increase the shelf life of the slide for analysis, B1 morning), the surface of the crackers is processed 1, 5-2.2% solution or a suspension of 2,6-di-tert-butyl-p-cresol prepared in a lacquer or acetone.
    U66664
    Table 1
    Time of occurrence of the first signs of blue, min
    Control slide (coated with pure acetone) Vanillin
    1-Phenylsemicarbazide 4-Phenylsemic arb azide 4-Phenyl-3-thiosemi-carbazide BHT
    5 5 5 5
    5,240
    Table 2
    权利要求:
    Claims (1)
    [1]
    Formula invented and
    A method of stabilizing a slide for analysis for the latent presence of blood by using panels equipped with holes and swivels. lids that cover these openings, characterized in that, in order to increase the shelf life of the slide for analysis, the inner surface of the lids is treated with a 1.5-2.2% solution or suspension of 2,6-di-tert-butyl-p -cresol prepared in varnish or acetone.
    g i
    The manifestation time of the first signs of a blue tint, min
    10 Control slide (coated with pure acetone) 5 Vanillin 5 1-phenylsemicarbazide 5 4-phenylsemicarbazide 5 fifteen 4-phenyl-3-thiosemiumcarbazide 5 VNT 240
    Table 2 BHT, mg (end- Development time concentrated concentration coloring days tion) 0 2 0.6 20 ',5 27
    类似技术:
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    SU1466664A3|1989-03-15|Method of stabilizing side for analysis for latent presence of blood
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    HU186012B|1985-05-28|Sample examining plate and process for determining blood-content with applying the sample examining plates
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    Wei et al.1974|Synthesis of ochratoxins TA and TC, analogs of ochratoxins A and C
    Emmett et al.1941|Determination of Vitamin B2 |: Comparison of Bioassay, Microbiological, and Fluorometric Methods
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    同族专利:
    公开号 | 公开日
    JPH0222908B2|1990-05-22|
    US4329317A|1982-05-11|
    IE52263B1|1987-08-19|
    HK56088A|1988-07-29|
    PT74334A|1982-02-01|
    FI73087C|1987-08-10|
    RO83668B1|1984-04-30|
    AT11081T|1985-01-15|
    NO157474B|1987-12-14|
    NO820266L|1982-07-30|
    RO83668A2|1984-04-02|
    GR74729B|1984-07-10|
    AU7980082A|1982-08-05|
    ES8304308A1|1983-02-16|
    PH18993A|1985-11-29|
    DD202214A5|1983-08-31|
    FI73087B|1987-04-30|
    ES509126A0|1983-02-16|
    DK33382A|1982-07-30|
    IE820186L|1982-07-29|
    KR880001337B1|1988-07-25|
    NO157474C|1988-03-23|
    JPS57144461A|1982-09-07|
    DK154857B|1988-12-27|
    PL129637B1|1984-05-31|
    IL64838D0|1982-03-31|
    PT74334B|1983-08-08|
    HU185504B|1985-02-28|
    EP0057542A1|1982-08-11|
    PL235119A1|1982-10-25|
    FI820207L|1982-07-30|
    DE3261721D1|1985-02-14|
    CA1170962A|1984-07-17|
    ZA82549B|1983-01-26|
    EP0057542B1|1985-01-02|
    CS236671B2|1985-05-15|
    KR830008659A|1983-12-14|
    IL64838A|1985-07-31|
    DK154857C|1989-05-16|
    AU552886B2|1986-06-26|
    NZ199560A|1985-03-20|
    引用文献:
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    US3933594A|1974-08-16|1976-01-20|Polaroid Corporation|Method and device for determining the concentration of a substance in a fluid|
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    DE2716060C3|1977-04-09|1980-06-12|Boehringer Mannheim Gmbh, 6800 Mannheim|Stabilized rapid diagnostics with oxidation indicators|
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    DE2853300C3|1978-12-09|1982-12-02|Röhm GmbH, 6100 Darmstadt|Rapid diagnostics for the diagnostic detection of occult blood|US4382064A|1981-01-29|1983-05-03|Smithkline Instruments, Inc.|Specimen slide for occult blood testing|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    US06/229,430|US4329317A|1981-01-29|1981-01-29|Method of stabilizing a specimen slide for occult blood testing|
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